Phagocytosis

Several types of cells in the immune system engulf microorganisms Phagocytosis.
-Neutrophil: are abundant in the blood, quickly enter tissues, and phagocytize pathogens in acute inflammation.



Macrophages: are closely related to monocytes in the blood. These cells predominate in chronic inflammation. They also release some important inflammatory chemicals.



B Lymphocytes: Phagocytosis in these cells is important for the elaboration of a specific immune response rather than for directly destroying the pathogens. (Activity 2).





Phagocytosis begins with the neutrophil or macrophage flowing around the pathogen and engulfing it so that it winds up enclosed in phagocytic vesicle.

commons.wikimedia.org/wiki/File:Phagocytosis2.png

The next step is the fusion of lysosomes with the phagosome. The result is called a phagolysosome. Lysosome are derived from the Golgi apparatus, much like secretion vesicles, but their contents are focused on destroying microorganisms.

And finally the cell will lyse the pathogen and eliminate it out if the body.

Sometimes the pathogen is strong than the macrophage or neutrophil.

What will be the next line of defense?